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  • 23 NOVEMBER 2024
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Study identifies new genetic form of Alzheimer's

The investigation was published this Monday in the magazine Nature Medicine. This genetic alteration may be present in 2% to 3% of the population.

Study identifies new genetic form of Alzheimer's
Notícias ao Minuto

12:40 - 07/05/24 por Notícias ao Minuto

Lifestyle Alzheimer

A new study by the Sant Pau Research Institute in Barcelona, Spain, reveals that there may be a new genetic form of Alzheimer's. The research was published in the journal Nature Medicine on Monday.

They found that more than 95% of people over 65 who have two copies of the APOE4 gene show biological signs of Alzheimer's disease. They also tend to develop the disease earlier than those with other variants of the gene, they explained.

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As such, they suggest that having two copies of this gene could represent a new genetic form of the disease. "This gene has been known for more than 30 years and was associated with an increased risk of developing Alzheimer's," explained Juan Fortea, one of the study's leaders.

"Now we know that practically all people who have this duplicated gene develop the biology of Alzheimer's. This is important because they represent between 2% and 3% of the population," he continued.

"The data clearly show that having two copies of the APOE4 gene not only increases the risk, but also precipitates the onset of Alzheimer's disease, reinforcing the need for specific preventive strategies," explained Alberto Lleó, a researcher at the Sant Pau Institute.

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